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Source- BBC NEWS      

12/17/01                               

Restoring Vision Through Cell Transplant

Scientists in the United Kingdom have developed a method that could lead to a treatment for age-related macular degeneration (AMD), a disease in which retinal pigment epithelial (RPE), cells that support the retina, lose their function.  The scientists transplanted human RPE cells to restore vision to rats whose retina degenerated after birth.  The experiment is published in the journal Nature Neuroscience.   

Source- Detroit Free Press

12/6/01

Creating The Perfect Christmas Tree

Scientists in North Carolina are using cross breeding and genetic engineering to create Christmas trees that are taller, bushier, less likely to lose needles, and more resistant to disease.

North Carolina State University researchers were the first to clone Fraser firs in the mid-1980's, the most popular Christmas tree in the country.

Cloning trees means cutting from a plant and use it to grow a replica. In some plants, such as geraniums, the procedure involves sticking a section of the stem in soil and letting it take root. However, it is more difficult with trees. For example, with Fraser firs, it involves chopping adult trees to knee-level, wait for the stumps to sprout green shoots, clipping the shoots and growing them in a greenhouse. Hormones are then added to the shoots until they grow their own roots. A slight change in temperature or humidity can prevent the roots from growing.

Source- Daily News

11/25/01

Cloning Human Embryo

A company, Advanced Cell Technology, located in Massachusetts has announced that it has cloned an embryo for stem cells used to treat diseases.

Embryonic stem cells can grow into any kind of specific cells/tissue in the body. Researchers removed the DNA from an egg cell and replaced it with DNA from the nucleus of the adult cell. The egg began to divide in a similar way as if it had been fertilized by a sperm. However, it did not continue to become a fetus. The same technology was used to clone sheep and cattle.

The procedure drew a lot of controversy.  The company stressed that the method was done only for the purpose of cloning cells and tissues- a technique that will result in producing treatments for many diseases, such as diabetes, Parkinson's, AIDS and cancer. However, the company admitted that if the cloned cells, or embryo, were placed in a woman's womb, it could possibly have grown into a human being!

Source- BBC News

11/18/01

A Blood Test For Down's Syndrome

A simple blood test was developed by Chinese scientists that screens for Down's syndrome. The blood is taken from pregnant women and screened using a technique called fluorescence in-situ hybridization (FISH).

Down's syndrome patients have a trisomy (three copies) of chromosome 21 as opposed to the normal two copies.

The current screening of the syndrome is through invasive techniques, known as amniocentesis or chorionic villus sampling. Both involve removal of tissue from the developing fetus for analysis.

Women who test positive for the syndrome should get proper counseling and support.

The study was published in the medical journal Lancet.

Source- Guardian Unlimited

11/16/01

A Gene That Makes Forget-Me-Not Remember

Scientists at the John Innes Centre at Norwich, England, have found a gene, VRN2 (known as vernalisation), that allows plants to "remember" a period of cold weather.

Vernalisation is when flowering occurs following a cold period of cold temperatures. The gene sequence was identified from a tiny weed, a member of the mustard family. 

The experiments demonstrated that if the plant was kept in the cold for a month and then moved to the warmth, flowering was accelerated because of the VRN2 gene which provided memory for the plant.

The study was published in the prestigious journal, Cell.

Source- Yahoo-Biotechnology Online

11/11/01

Two Genes Work Together To Promote Breast Cancer

Scientists at the Netherlands Cancer Institute in Amsterdam studied the relationship between two genes, p53 and BRCA2 in promoting breast cancer.

Mice genetically engineered to carry defects in both p53 and BRCA2 had a high rate of developing tumors than mice with only one defective gene.

p53 gene is important in instructing abnormal cells to kill themselves. In more than half of all cancers, p53 is defective and abnormal cells are allowed to grow into tumors. BRCA2 gene is known to play a role in about one third of all hereditary breast cancers. 

Source- Allafrica.com

11/01/01

Genetically Modified Maize and Potatoes

Scientists at Kenya Agriculture and Research Institute (Kari) have developed a variety of genetically modified potato and maize that are disease-resistant and could have better yield.

The two crops are among the major staple foods consumed in Kenya, Africa. This could help the country in alleviating poverty among their people.

The modified crops are undergoing trials and biosafety measures at various Kari stations.  

 

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